195966-93-9
195966-93-9
Chemical Structure
(rel)-Asperparaline A
Synonym(s): (rel)-Aspergillimide; (rel)-VM55598
- CAS No.: 195966-93-9
- Formula:C20H29N3O3
- Molecular Weight:359.46
SMILES: CN(C1=O)C(C[C@@]2(CC3=O)C(N3C)=O)(CN(CC[C@@H]4C)C14C5)[C@]5([H])C2(C)C.[Rotation (-)]
Biological Activity: (rel)-Asperparaline A ((rel)-Aspergillimide), an anthelmintic metabolite, is isolated from okara that has been fermented with Aspergillus japonicas JV-23. (rel)-Asperparaline A is also a potent and selective antagonist of nAChR. (rel)-Asperparaline A exhibits paralytic activity in silk worms[1][2].
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(rel)-Asperparaline A | (rel)-Asperparaline A ((rel)-Aspergillimide), an anthelmintic metabolite, is isolated from okara that has been fermented with Aspergillus japonicas JV-23. (rel)-Asperparaline A is also a potent and selective antagonist of nAChR. (rel)-Asperparaline A exhibits paralytic activity in silk worms. | |||||||||||||||||||||
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References
- [1]. Hayashi H, et, al. New paralytic alkaloids, asperparalines A, B and C, from Aspergillus japonicus JV-23. Biosci Biotechnol Biochem. 2000 Jan;64(1):111-5. [Content Brief]
- [2]. Hirata K, et, al. A fungal metabolite asperparaline a strongly and selectively blocks insect nicotinic acetylcholine receptors: the first report on the mode of action. PLoS One. 2011 Apr 1;6(4):e18354. [Content Brief]
