1965323-05-0
Chemical Structure
Syk Inhibitor II dihydrochloride dihydrate
- CAS No.: 1965323-05-0
- Formula:C14H21Cl2F3N6O3
- Molecular Weight:449.26
IUPAC Name: 2-((2-aminoethyl)amino)-4-((3-(trifluoromethyl)phenyl)amino)pyrimidine-5-carboxamide dihydrochloride dihydrate
InChIKey: LCACSMNPIITJGG-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(NCCN)N=C1NC2=CC=CC(C(F)(F)F)=C2)N.[H]Cl.[H]Cl.O.O
Biological Activity: Syk Inhibitor II dihydrochloride dihydrate is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride dihydrate inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride dihydrate shows less potent against other kinases and has anti-allergic effect[1].
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Syk Inhibitor II dihydrochloride dihydrate | Syk Inhibitor II dihydrochloride dihydrate is a potent, high selective and ATP-competitive Syk inhibitor with an IC50 of 41 nM. Syk Inhibitor II dihydrochloride dihydrate inhibits 5-HT release from RBL-cells with an IC50 of 460 nM. Syk Inhibitor II dihydrochloride dihydrate shows less potent against other kinases and has anti-allergic effect. | |||||||||||||||||||||
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