19703-86-7
19703-86-7
Chemical Structure
LU 2443
- CAS No.: 19703-86-7
- Formula:C9H8N2S2
- Molecular Weight:208.30
IUPAC Name: 4-methyl-5-phenyl-2-thioxo-1,3,4-thiadiazol-4-ium-3-ide
InChIKey: KKABNDWCHGAGAZ-UHFFFAOYSA-N
SMILES: S=C1SC(C2=CC=CC=C2)=[N+](C)[N-]1
Biological Activity: LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h[1].
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LU 2443 | LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h. | |||||||||||||||||||||
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References
- [1]. Neidlein R, et al. Biotransformation und Pharmakokinetik von mesoionischem Didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidin-2-thion (LU 2443). Untersuchungen zur Pharmakokinetik an Ratten [Biotransformation and pharmacokinetics of mesionic didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidine-2-thione (LU 2443). Studies on the pharmacokinetics in rats]. Arzneimittelforschung. 1982;32(11):1447-52. [Content Brief]
