19916-77-9
19916-77-9
Chemical Structure
2′-Deoxy-N-methylguanosine
- CAS No.: 19916-77-9
- Formula:C11H15N5O4
- Molecular Weight:281.27
IUPAC Name: 9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-(methylamino)-1,9-dihydro-6H-purin-6-one
InChIKey: XEZUVZDXOQPEKT-RRKCRQDMSA-N
SMILES: O[C@H]1C[C@H](N2C(N=C(NC)NC3=O)=C3N=C2)O[C@@H]1CO
Biological Activity: 2’-Deoxy-N2-methylguanosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2′-Deoxy-N-methylguanosine | 99.82% | 2’-Deoxy-N2-methylguanosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | ||||||||||||||||||||
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N2-Methylguanosine (Standard) | ≥98% | N2-Methylguanosine (Standard) is the analytical standard of N2-Methylguanosine (HY-111647). This product is intended for research and analytical applications. N2-Methylguanosine is a commonly modified nucleoside in rRNA and tRNA, with specific distributions in both E. coli rRNA and eukaryotic tRNA. N2-Methylguanosine can be found in urine. N2-Methylguanosine affects the structure and stability of RNA. | ||||||||||||||||||||
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2-Chloro-2’-deoxy inosine | 2-Chloro-2’-deoxy inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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2’-Deoxy-N2,N2-dimethylguanosine | 2’-Deoxy-N2,N2-dimethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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2'-Deoxy-N2-isopropyl guanosine | 2’-Deoxy-N2-isopropyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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2'-Deoxy-N2,N2-diethyl guanosine | 2’-Deoxy-N2,N2-diethyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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2'-Deoxyguanosine (Standard) | 99.21% | 2'-Deoxyguanosine (Standard) is the analytical standard of 2'-Deoxyguanosine. This product is intended for research and analytical applications. 2’-Deoxyguanosine (Deoxyguanosine) is a purine nucleoside with a variety of biological activities. 2’-Deoxyguanosine can induce DNA division in mouse thymus cells. 2’-Deoxyguanosine is a potent cell division inhibitor in plant cells.
In Vitro: 2'-Deoxyguanosine inhibits the clonal growth of HL-60 and K562 leukemia cells with IC50 values of 50 and 80 μM, respectively. |
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2'-Deoxyguanosine-13C10,15N5 | 2'-Deoxyguanosine-13C10,15N5 (Deoxyguanosine-13C10,15N5; Guanine deoxyriboside-13C10,15N5) is a 13C- and 15N-labeled 2'-Deoxyguanosine (HY-17563). | |||||||||||||||||||||
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2'-Deoxyguanosine-13C10 | 99.8% | 2'-Deoxyguanosine-13C10 (Deoxyguanosine-13C10; Guanine deoxyriboside-13C10) is 13C-labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine. | ||||||||||||||||||||
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2'-Deoxyguanosine-15N5 | 99.80% | 2'-Deoxyguanosine-15N5 (Deoxyguanosine-15N5; Guanine deoxyriboside-15N5) is 15N labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine. | ||||||||||||||||||||
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2'-Deoxyguanosine monohydrate | 99.70% | 2'-Deoxyguanosine monohydrate is a nucleoside composed of guanine and 2'-deoxyribose, and it is one of the basic structural units of DNA. The oxidation products of 2'-Deoxyguanosine monohydrate may participate in DNA damage, which in turn may affect gene expression or induce cancer. | ||||||||||||||||||||
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