199798-84-0
Chemical Structure
Elocalcitol
Synonym(s): BXL-628; Ro-26-9228
- CAS No.: 199798-84-0
- Formula:C29H43FO2
- Molecular Weight:442.65
IUPAC Name: (1R,5S,Z)-3-(2-((3aS,7aS,E)-1-((S,E)-6-ethyl-6-hydroxyoct-4-en-2-yl)-7a-methyl-3,3a,5,6,7,7a-hexahydro-4H-inden-4-ylidene)ethylidene)-5-fluoro-4-methylenecyclohexan-1-ol
InChIKey: LRLWXBHFPGSUOX-GJQYOBCGSA-N
SMILES: C[C@@]12[C@](CC=C2[C@@H](C)C/C=C/C(CC)(O)CC)([H])/C(CCC1)=C/C=C3C([C@H](C[C@@H](C\3)O)F)=C
Biological Activity: Elocalcitol (BXL-628), a vitamin D analogue, is a selective, orally active vitamin D receptor (VDR) agonist. Elocalcitol shows anti-inflammatory activity. Elocalcitol inhibits growth of prostate cancer cells[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Elocalcitol | 99.15% | Elocalcitol (BXL-628), a vitamin D analogue, is a selective, orally active vitamin D receptor (VDR) agonist. Elocalcitol shows anti-inflammatory activity. Elocalcitol inhibits growth of prostate cancer cells. | ||||||||||||||||||||
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References
- [1]. Mariani M, et al. The selective vitamin D receptor agonist, elocalcitol, reduces endometriosis development in a mouse model by inhibiting peritoneal inflammation. Hum Reprod. 2012 Jul;27(7):2010-9. [Content Brief]
- [2]. Marchiani S, et al. The vitamin D analogue BXL-628 inhibits growth factor-stimulated proliferation and invasion of DU145 prostate cancer cells. J Cancer Res Clin Oncol. 2006 Jun;132(6):408-16. [Content Brief]
