200496-85-1
200496-85-1
Chemical Structure
Epoxyquinomicin C
- CAS No.: 200496-85-1
- Formula:C14H13NO6
- Molecular Weight:291.26
InChIKey: JNDISHBDOZQLTR-SCRDCRAPSA-N
SMILES: OC[C@]12[C@]([C@H](C(NC(C3=C(C=CC=C3)O)=O)=CC2=O)O)([H])O1
Biological Activity: Epoxyquinomicin C is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin C exhibits anti-inflammatory effects against collagen-induced arthritis. Epoxyquinomicin C can be designed for synthesis of the NF-κB Inhibitor DHMEQ[1][2].
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Epoxyquinomicin C | Epoxyquinomicin C is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin C exhibits anti-inflammatory effects against collagen-induced arthritis. Epoxyquinomicin C can be designed for synthesis of the NF-κB Inhibitor DHMEQ. | |||||||||||||||||||||
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References
- [1]. Matsumoto N, et al., Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. I. Taxonomy, fermentation, isolation and antimicrobial activities. J Antibiot (Tokyo). 1997 Nov;50(11):900-5. [Content Brief]
- [2]. Lin Y, et al., Inhibition of Late and Early Phases of Cancer Metastasis by the NF-κB Inhibitor DHMEQ Derived from Microbial Bioactive Metabolite Epoxyquinomicin: A Review. Int J Mol Sci. 2018 Mar 3;19(3):729. [Content Brief]
