2010159-60-9
2010159-60-9
Chemical Structure
(S,R,S)-AHPC-PEG2-NH2
Synonym(s): VH032-PEG2-NH2 ; VHL Ligand-Linker Conjugates 3 ; E3 ligase Ligand-Linker Conjugates 6 Free Base
- CAS No.: 2010159-60-9
- Formula:C28H41N5O6S
- Molecular Weight:575.72
IUPAC Name: (2S,4R)-1-((S)-2-(2-(2-(2-aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: XWDVNBVOCHHWAD-OTNCWRBYSA-N
SMILES: O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
Biological Activity: (S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1].
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(S,R,S)-AHPC-PEG2-NH2 | 98.06% | (S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs. | ||||||||||||||||||||
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(S,R,S)-AHPC-PEG2-NH2 (Standard) | ≥98% | (S,R,S)-AHPC-PEG2-NH2 (Standard) is the analytical standard of (S,R,S)-AHPC-PEG2-NH2 (HY-103603A). This product is intended for research and analytical applications. (S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs. | ||||||||||||||||||||
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(S,R,S)-AHPC-PEG3-NH2 hydrochloride | 99.01% | (S,R,S)-AHPC-PEG3-NH2 (VH032-PEG3-NH2) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. | ||||||||||||||||||||
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(S,R,S)-AHPC-PEG3-NH2 | 99.26% | (S,R,S)-AHPC-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology. | ||||||||||||||||||||
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(S,R,S)-AHPC-PEG3-NH2 dihydrochloride | (S,R,S)-AHPC-PEG3-NH2 dihydrochloride (VH032-PEG3-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker used in PROTAC technology | |||||||||||||||||||||
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(S,R,S)-AHPC-PEG2-NH2 dihydrochloride | (S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-PEG2-NH2 dihydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs. | |||||||||||||||||||||
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(S,S,S)-AHPC-PEG2-NH2 | (S,S,S)-AHPC-PEG2-NH2 is an isomer of Compound 15b. Compound 15b is a conjugate of a VHL ligand and linker. Compound 15b can be used to synthesize PROTAC. Compound 15b can be used in leukemia research. | |||||||||||||||||||||
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(S,R,S)-AHPC-PEG2-NH2 hydrochloride (Standard) | ≥98% | (S,R,S)-AHPC-PEG2-NH2 hydrochloride (Standard) is the analytical standard of (S,R,S)-AHPC-PEG2-NH2 hydrochloride (HY-103603). This product is intended for research and analytical applications. (S,R,S)-AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs. | ||||||||||||||||||||
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(S,R,S)-AHPC-PEG1-NH2 | 98.48% | (S,R,S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. | ||||||||||||||||||||
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(S,R,S)-AHPC-PEG1-NH2 dihydrochloride | (S,R,S)-AHPC-PEG1-NH2 (VH032-PEG1-NH2) dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker. (S,R,S)-AHPC-PEG1-NH2 dihydrochloride can be used to design PROTACs. | |||||||||||||||||||||
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(S,R,S)-AHPC-Amide-PEG2-C2-NH2 | 97.16% | (S,R,S)-AHPC-Amide-PEG2-C2-NH2 is an E3 Ligase Ligand-Linker Conjugates that can be used to synthesize PROTAC PI3K/110β degrader-1 (HY-176421). | ||||||||||||||||||||
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(S,R,R)-VH032-CO-PEG2-NH2 | (S,R,R)-VH032-CO-PEG2-NH2 is a conjugate of an E3 ligand and a linker, which can be used for the synthesis of PROTACs, such as UNC8899 (HY-158046). | |||||||||||||||||||||
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