202914-21-4
202914-21-4
Chemical Structure
CHF-2993
- CAS No.: 202914-21-4
- Formula:C12H16N2O2
- Molecular Weight:220.27
IUPAC Name: (S)-2-((2,3-dihydro-1H-inden-2-yl)amino)-3-hydroxypropanamide
InChIKey: MZRNXGZQIIFZTC-NSHDSACASA-N
SMILES: N([C@H](C(N)=O)CO)C1CC=2C(C1)=CC=CC2
Biological Activity: CHF-2993 is an orally active anticonvulsant. CHF-2993 antagonizes Bicuculline (HY-N0219)- and Picrotoxin (HY-101391)-induced tonic convulsions in mice, shows no activity against Pentylenetetrazole-induced clonic convulsions in mice, and partially reduces Veratridine (HY-N6691)-induced aspartate efflux in rat cortical synaptosomes. CHF-2993 can be used in the research of epilepsy[1].
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CHF-2993 | CHF-2993 is an orally active anticonvulsant. CHF-2993 antagonizes Bicuculline (HY-N0219)- and Picrotoxin (HY-101391)-induced tonic convulsions in mice, shows no activity against Pentylenetetrazole-induced clonic convulsions in mice, and partially reduces Veratridine (HY-N6691)-induced aspartate efflux in rat cortical synaptosomes. CHF-2993 can be used in the research of epilepsy. | |||||||||||||||||||||
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