20312-37-2
20312-37-2
Chemical Structure
(R)-Leucic acid
Synonym(s): D-α-Hydroxyisocaproic acid
- CAS No.: 20312-37-2
- Formula:C6H12O3
- Molecular Weight:132.16
IUPAC Name: (R)-2-hydroxy-4-methylpentanoic acid
InChIKey: LVRFTAZAXQPQHI-RXMQYKEDSA-N
SMILES: O=C(O)[C@H](O)CC(C)C
Biological Activity: (R)-Leucic acid (D-α-Hydroxyisocaproic acid) is an orally active D-isomer of the α-hydroxy analogue of Leucine (HY-N0486). (R)-Leucic acid is a metabolite of Lactobacillus and can promote intestinal fatty acid absorption by upregulating CD36 expression. (R)-Leucic acid can be used to study microbe-host interactions and the regulation of lipid metabolism by probiotics[1][2].
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(R)-Leucic acid | 98.0% | (R)-Leucic acid (D-α-Hydroxyisocaproic acid) is an orally active D-isomer of the α-hydroxy analogue of Leucine (HY-N0486). (R)-Leucic acid is a metabolite of Lactobacillus and can promote intestinal fatty acid absorption by upregulating CD36 expression. (R)-Leucic acid can be used to study microbe-host interactions and the regulation of lipid metabolism by probiotics. | ||||||||||||||||||||
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(R)-Leucic acid (Standard) | 99.92% | (R)-Leucic acid (Standard) is the analytical standard of (R)-Leucic acid (HY-30216). This product is intended for research and analytical applications. (R)-Leucic acid (D-α-Hydroxyisocaproic acid) is the D-isomer of the α-hydroxy analogue of Leucine (HY-N0486). (R)-Leucic acid is a metabolite of Lactobacillus and can promote intestinal fatty acid absorption by upregulating CD36 expression. (R)-Leucic acid can be used to study microbe-host interactions and the regulation of lipid metabolism by probiotics. | ||||||||||||||||||||
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References
- [1]. Li Y, et al. Lactobacillus johnsonii-derived leucic acid promotes fatty acid absorption and deposition by targeting CD36. Sci China Life Sci. 2025 Jun;68(6):1727-1739. [Content Brief]
- [2]. Boebel KP, Baker DH. Comparative utilization of the α-keto and D-and L-α-hydroxy analogs of leucine, isoleucine and valine by chicks and rats. The Journal of nutrition. 1982 Oct 1;112(10):1929-39.
