2033173-00-9
2033173-00-9
Chemical Structure
(R)-IDO/TDO-IN-1
- CAS No.: 2033173-00-9
- Formula:C25H24FN5
- Molecular Weight:413.49
InChIKey: UJGQDAMZVUNFBQ-RUZDIDTESA-N
SMILES: CN1N=CC(C2=CC=C(N3CCC([C@H](C4=C5C=CC=C4F)N6C5=CN=C6)CC3)C=C2)=C1
Biological Activity: (R)-IDO/TDO-IN-1 (compound 25) is an indoleamine-2,3-dioxygenase (IDO) inhibitor, with good pharmacokinetic properties. (R)-IDO/TDO-IN-1 exhibits anti-tumor activity in MC38 xenograft model. (R)-IDO/TDO-IN-1 shows synergistic effect with anti-PD-1 monoclonal antibody (SHR-1210)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(R)-IDO/TDO-IN-1 | 98.04% | (R)-IDO/TDO-IN-1 (compound 25) is an indoleamine-2,3-dioxygenase (IDO) inhibitor, with good pharmacokinetic properties. (R)-IDO/TDO-IN-1 exhibits anti-tumor activity in MC38 xenograft model. (R)-IDO/TDO-IN-1 shows synergistic effect with anti-PD-1 monoclonal antibody (SHR-1210). | ||||||||||||||||||||
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