2035069-96-4
2035069-96-4
Chemical Structure
CDK4/6-IN-17
- CAS No.: 2035069-96-4
- Formula:C27H28F4N8
- Molecular Weight:540.56
InChIKey: LOWCJOWTSOHEME-FQEVSTJZSA-N
SMILES: FC([C@H]1N2C3=CC(C4=NC(NC5=CC=C(C=N5)CN6CCN(CC6)CC)=NC=C4F)=CC(F)=C3N=C2CC1)F
Biological Activity: CDK4/6-IN-17 (compound 12) is an orally active CDK4/6 inhibitor with IC50 ranging of 10-100 nM in BE(2) cells. CDK4/6-IN-17 inhibits tumor growth in COLO205 xenograft model[1].
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CDK4/6-IN-17 | CDK4/6-IN-17 (compound 12) is an orally active CDK4/6 inhibitor with IC50 ranging of 10-100 nM in BE(2) cells. CDK4/6-IN-17 inhibits tumor growth in COLO205 xenograft model. | |||||||||||||||||||||
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