204398-91-4
Chemical Structure
Drimentine B
- CAS No.: 204398-91-4
- Formula:C31H39N3O2
- Molecular Weight:485.66
IUPAC Name: (5aS,6aS,11aS)-6a-(((1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydronaphthalen-1-yl)methyl)-2,3,6,6a,11,11a-hexahydro-13H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-5,13(5aH)-dione
InChIKey: SUUCBHITXBJOGT-JMGSXGSMSA-N
SMILES: O=C(N1C2=CCC1)[C@@]([H])(N3C2=O)C[C@@]4([C@]3(NC5=C4C=CC=C5)[H])C[C@]6(C(CC[C@@]7([C@@]6(CCCC7(C)C)C)[H])=C)[H]
Biological Activity: Drimentine B is a terpenylated diketopiperazine originally isolated from Actinomycete bacteria that has anticancer activity. It inhibits the proliferation of NS-1 murine β lymphocyte myeloma cells by 41 and 59% in vitro when used at concentrations of 50 and 100 μg/mL, respectively.
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Drimentine B | Drimentine B is a terpenylated diketopiperazine originally isolated from Actinomycete bacteria that has anticancer activity. It inhibits the proliferation of NS-1 murine β lymphocyte myeloma cells by 41 and 59% in vitro when used at concentrations of 50 and 100 μg/mL, respectively. | |||||||||||||||||||||
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