2050595-03-2
Chemical Structure
m-PEG12-OH
- CAS No.: 2050595-03-2
- Formula:C25H52O13
- Molecular Weight:560.67
IUPAC Name: 2,5,8,11,14,17,20,23,26,29,32,35-dodecaoxaheptatriacontan-37-ol
InChIKey: PLQZJIIDLZRWBG-UHFFFAOYSA-N
SMILES: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
Biological Activity: m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
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m-PEG12-OH | 100.00% | m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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Propargyl-PEG12-OH | Propargyl-PEG12-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG12-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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m-PEG12-acid | 99.12% | m-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Propargyl-PEG11-methane | Propargyl-PEG11-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Propargyl-PEG11-methane is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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Amino-PEG12-alcohol | 99.78% | Amino-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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m-PEG12-amine | 99.71% | m-PEG12-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-amine is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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m-PEG11-OH | 99.83% | m-PEG11-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Dodecaethylene glycol | 99.93% | Dodecaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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HO-PEG13-OH | 97.0% | HO-PEG13-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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m-PEG12-Thiol | 95.0% | m-PEG12-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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m-PEG12-Br | m-PEG12-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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References
- [1]. Kachbi-Khelfallah S, et al. Towards potential nanoparticle contrast agents: Synthesis of new functionalized PEG bisphosphonates. Beilstein J Org Chem. 2016 Jul 4;12:1366-71. [Content Brief]
- [2]. Hamura, Mika, et al. Branched monodispersed polyethylene glycol, intermediate, and method for producing same. WO 2019181984 A1.