2055172-43-3
2055172-43-3
Chemical Structure
ML-226
- CAS No.: 2055172-43-3
- Formula:C23H26N4O2
- Molecular Weight:390.48
IUPAC Name: (2-ethylpiperidin-1-yl)(4-(hydroxydiphenylmethyl)-2H-1,2,3-triazol-2-yl)methanone
InChIKey: DGRUIUDIVFCWMX-UHFFFAOYSA-N
SMILES: O=C(N1C(CC)CCCC1)N2N=CC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)=N2
Biological Activity: ML226 is a potent inhibitor of α/β hydrolase domain protein 11 (ABHD11), with in vitro and in situ IC50 values of 15 and 0.68 nM, respectively. ML226 is an inhibitor of protein palmitoylthioesterase lysophospholipase 1 (LYPLA1) and LYPLA2. ML226 can be used for research related to neurological diseases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ML-226 | 98.76% | ML226 is a potent inhibitor of α/β hydrolase domain protein 11 (ABHD11), with in vitro and in situ IC50 values of 15 and 0.68 nM, respectively. ML226 is an inhibitor of protein palmitoylthioesterase lysophospholipase 1 (LYPLA1) and LYPLA2. ML226 can be used for research related to neurological diseases. | ||||||||||||||||||||
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References
- [1]. Hsu KL, et al. Optimization and characterization of triazole urea inhibitors for abhydrolase domain containing protein 6 (ABHD6). 2012 Apr 12 [updated 2013 Mar 14]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. [Content Brief]
