2058264-32-5
2058264-32-5
Chemical Structure
TBK1/IKKε-IN-1
- CAS No.: 2058264-32-5
- Formula:C28H26N4O5
- Molecular Weight:498.53
IUPAC Name: 6-(7-(3-cyano-4-((tetrahydro-2H-pyran-4-yl)oxy)phenyl)furo[3,2-b]pyridin-2-yl)-5-methoxy-N,N-dimethylnicotinamide
InChIKey: QHZNENVHULXUOO-UHFFFAOYSA-N
SMILES: O=C(C1=CC(OC)=C(C2=CC3=NC=CC(C4=CC=C(OC5CCOCC5)C(C#N)=C4)=C3O2)N=C1)N(C)C
Biological Activity: TBK1/IKKε-IN-1 is a dual TBK1 and IKKε inhibitor extracted from patent US20160376283 A1, Compound 274 in Example 60, has IC50s of <100 nM.
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TBK1/IKKε-IN-1 | TBK1/IKKε-IN-1 is a dual TBK1 and IKKε inhibitor extracted from patent US20160376283 A1, Compound 274 in Example 60, has IC50s of <100 nM. | |||||||||||||||||||||
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