2070009-24-2
2070009-24-2
Chemical Structure
Calcitriol Derivatives
- CAS No.: 2070009-24-2
- Formula:C30H47NO3
- Molecular Weight:469.70
IUPAC Name: 3-(((1R,3S,Z)-3-hydroxy-5-(2-((1R,3aS,7aR,E)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexyl)oxy)propanenitrile
InChIKey: JEXMJWGETRFCMK-MSCDRTKFSA-N
SMILES: O[C@H](C/1=C)C[C@@H](CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](CCCC(C)(O)C)C)([H])[C@]3(C)CCC\2)OCCC#N
Biological Activity:
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Calcitriol Derivatives | 99.55% | Calcitriol Derivatives is a vitamin D3 analog. | ||||||||||||||||||||
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References
- Barrera D, Noyola-Martínez N, Avila E, Halhali A, Larrea F, Díaz L. Calcitriol inhibits interleukin-10 expression in cultured human trophoblasts under normal and inflammatory conditions. Cytokine. 2012 Mar;57(3):316-21. [Content Brief]
- Lydia A, Asanuma K, Nonaka K, Takagi M, Jeong KH, Kodama F, Asao R, Asanuma E, Prodjosudjadi W, Tomino Y. Effects of 22-oxa-calcitriol on podocyte injury in adriamycin-induced nephrosis. Am J Nephrol. 2012;35(1):58-68. [Content Brief]
- Michalak K, Wicha J. Total synthesis of a CD-ring: side-chain building block for preparing 17-epi-calcitriol derivatives from the Hajos-Parrish dione. J Org Chem. 2011 Aug 19;76(16):6906-11. [Content Brief]
- Moorthi RN, Kandula P, Moe SM. Optimal vitamin D, calcitriol, and vitamin D analog replacement in chronic kidney disease: to D or not to D: that is the question. Curr Opin Nephrol Hypertens. 2011 Jul;20(4):354-9. [Content Brief]
- Yu WD, Ma Y, Flynn G, Muindi JR, Kong RX, Trump DL, Johnson CS. Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system. Cell Cycle. 2010 Aug 1;9(15):3022-9. [Content Brief]
