2072051-04-6
2072051-04-6
Chemical Structure
TGFβRI-IN-6
- CAS No.: 2072051-04-6
- Formula:C17H10F4N6
- Molecular Weight:374.30
IUPAC Name: N-(3-fluoropyridin-4-yl)-2-(6-(trifluoromethyl)pyridin-2-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
InChIKey: KNTWBIUWHSYQJE-UHFFFAOYSA-N
SMILES: FC1=CN=CC=C1NC2=C(C=CN3)C3=NC(C4=NC(C(F)(F)F)=CC=C4)=N2
Biological Activity: TGFβRI-IN-6 (compound 22) is a potent TGFβRI inhibitor with an IC50 value of 0.55 nM. TGFβRI-IN-6 has the potential to enhance anti-tumor immunity[1].
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TGFβRI-IN-6 | TGFβRI-IN-6 (compound 22) is a potent TGFβRI inhibitor with an IC50 value of 0.55 nM. TGFβRI-IN-6 has the potential to enhance anti-tumor immunity. | |||||||||||||||||||||
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