207623-15-2
207623-15-2
Chemical Structure
ODN 1982
- CAS No.: 207623-15-2
- Formula:N/A
- Molecular Weight:6364.10
SMILES: [DNA, d(P-thio)(T-C-C-A-G-G-A-C-T-T-C-T-C-T-C-A-G-G-T-T)]
Biological Activity: ODN 1982 is a unmethylated oligodeoxyribonucleotide (ODN) with no CpG motif, can be used to prepare DNA vaccines. ODN 1982 inhibits R-848 signaling. ODN 1982 sequence: 5’-tccaggacttctctcaggtt-3’[1][2].
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ODN 1982 | ODN 1982 is a unmethylated oligodeoxyribonucleotide (ODN) with no CpG motif, can be used to prepare DNA vaccines. ODN 1982 inhibits R-848 signaling. ODN 1982 sequence: 5’-tccaggacttctctcaggtt-3’. | |||||||||||||||||||||
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References
- [1]. Tudor D, et al. TLR9 pathway is involved in adjuvant effects of plasmid DNA-based vaccines. Vaccine. 2005 Jan 26;23(10):1258-64. [Content Brief]
- [2]. Jurk M, et al. Modulating responsiveness of human TLR7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides. Eur J Immunol. 2006 Jul;36(7):1815-26. [Content Brief]
