2077182-79-5
Chemical Structure
Euphomilone A
- CAS No.: 2077182-79-5
- Formula:C20H32O3
- Molecular Weight:320.47
IUPAC Name: (2S,4aS,4bR,7R,9aR,10aS)-4b,7-dihydroxy-2,4a,8,8-tetramethyl-2-vinyldodecahydrobenzo[a]azulen-9(1H)-one
InChIKey: WYHLKCCBMRNDOB-LVNOUGRESA-N
SMILES: C[C@@]12[C@@]3([C@@](C(C(C)([C@@H](CC3)O)C)=O)([H])C[C@@]1([H])C[C@](C)(CC2)C=C)O
Biological Activity: Euphomilone A is an ent-abietane-type diterpenoid osteoclastogenesis inhibitor and RANK inhibitor, found in the aerial parts of Euphorbia milii, possessing a 7/5/6 tricyclic system. Euphomilone A inhibits RANKL-induced osteoclastogenesis in monocyte/macrophage lineage cells. Euphomilone A can be used in research on bone resorption-related diseases[1].
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Euphomilone A | Euphomilone A is an ent-abietane-type diterpenoid osteoclastogenesis inhibitor and RANK inhibitor, found in the aerial parts of Euphorbia milii, possessing a 7/5/6 tricyclic system. Euphomilone A inhibits RANKL-induced osteoclastogenesis in monocyte/macrophage lineage cells. Euphomilone A can be used in research on bone resorption-related diseases. | |||||||||||||||||||||
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