2087490-43-3
2087490-43-3
Chemical Structure
(Z)-JQ1-TCO
Synonym(s): JQ1-CCO
- CAS No.: 2087490-43-3
- Formula:C31H37ClN6O3S
- Molecular Weight:609.18
InChIKey: CYIPOINYTLBSLB-SBSQNJSVSA-N
SMILES: CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(NCCCNC(OC4CCC/C=C\CC4)=O)=O)C5=NN=C(C)N25
Biological Activity: (Z)-JQ1-TCO is a derivative of JQ1 (HY-13030), an inhibitor of BET. (Z)-JQ1-TCO is suitable for click chemistry and can be used as molecular probes in vitro and in vivo[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(Z)-JQ1-TCO | 99.12% | (Z)-JQ1-TCO is a derivative of JQ1 (HY-13030), an inhibitor of BET. (Z)-JQ1-TCO is suitable for click chemistry and can be used as molecular probes in vitro and in vivo. | ||||||||||||||||||||
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References
- [1]. Hu Z, et al. Recent Developments in PROTAC-Mediated Protein Degradation: From Bench to Clinic. Chembiochem. 2022 Jan 19;23(2):e202100270. [Content Brief]
- [2]. Tyler DS, et al. Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science. 2017 Jun 30;356(6345):1397-1401. [Content Brief]
