2088127-60-8
Chemical Structure
Mito-Cu(II)
- CAS No.: 2088127-60-8
- Formula:C32H27N3O
- Molecular Weight:469.58
InChIKey: QOHOFBCODGXHGI-CCEZHUSRSA-N
SMILES: OC1=CC(/C=C/C2=CC=C(N(C3=CC=CC=C3)C4=CC=CC=C4)C=C2)=CC=C1NCC5=NC=CC=C5
Biological Activity: Mito-Cu (II) is a mitochondria-targeted fluorescent probe (Ex/Em = 370/450 nM). Mito-Cu (II) specifically accumulates in mitochondria of living cells and enables real-time detection of exogenous Cu2+ within mitochondria of living cells. Mito-Cu (II) achieves "on-off-on" fluorescence switching through sequential exposure to Cu2+ and ethylenediaminetetraacetic acid (EDTA) (HY-Y0682). Its fluorescence is quenched after forming a 1:1 complex with Cu2+, and the fluorescence recovers when Cu2+ is chelated by EDTA[1].
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Mito-Cu(II) | Mito-Cu (II) is a mitochondria-targeted fluorescent probe (Ex/Em = 370/450 nM). Mito-Cu (II) specifically accumulates in mitochondria of living cells and enables real-time detection of exogenous Cu2+ within mitochondria of living cells. Mito-Cu (II) achieves "on-off-on" fluorescence switching through sequential exposure to Cu2+ and ethylenediaminetetraacetic acid (EDTA) (HY-Y0682). Its fluorescence is quenched after forming a 1:1 complex with Cu2+, and the fluorescence recovers when Cu2+ is chelated by EDTA. | |||||||||||||||||||||
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