2089056-09-5
Chemical Structure
A-395N
- CAS No.: 2089056-09-5
- Formula:C24H34N4O2S
- Molecular Weight:442.62
IUPAC Name: (3S,4R)-1-benzyl-N,N-dimethyl-4-(4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)pyrrolidin-3-amine
InChIKey: VEABDKBNQNHHCB-BJKOFHAPSA-N
SMILES: CN([C@H]1[C@H](C2=CC=C(N3CCN(CC3)S(C)(=O)=O)C=C2)CN(C1)CC4=CC=CC=C4)C
Biological Activity: A-395N serves as a control probe for A-395, a highly potent and selective chemical probe targeting the polycomb protein EED, a key player in Polycomb repressive complex 2 (PRC2) responsible for transcriptional repression via histone H3K27 methylation. While A-395N bears structural similarities to A-395, it demonstrates no pharmacological activity in biochemical or cellular assays, making it an ideal control compound.
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A-395N | A-395N serves as a control probe for A-395, a highly potent and selective chemical probe targeting the polycomb protein EED, a key player in Polycomb repressive complex 2 (PRC2) responsible for transcriptional repression via histone H3K27 methylation. While A-395N bears structural similarities to A-395, it demonstrates no pharmacological activity in biochemical or cellular assays, making it an ideal control compound. | |||||||||||||||||||||
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