2097416-76-5
2097416-76-5
Chemical Structure
Tizaterkib
Synonym(s): AZD0364
- CAS No.: 2097416-76-5
- Formula:C24H24F2N8O2
- Molecular Weight:494.50
IUPAC Name: (R)-7-(3,4-difluorobenzyl)-6-(methoxymethyl)-2-(5-methyl-2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)-6,7-dihydroimidazo[1,2-a]pyrazin-8(5H)-one
InChIKey: HVIGNZUDBVLTLU-MRXNPFEDSA-N
SMILES: O=C1C2=NC(C3=NC(NC4=CC=NN4C)=NC=C3C)=CN2C[C@H](COC)N1CC5=CC=C(F)C(F)=C5
Biological Activity: Tizaterkib (AZD0364) is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1, compound example 18, has an IC50 of 0.6 nM.
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Tizaterkib | 99.10% | Tizaterkib (AZD0364) is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1, compound example 18, has an IC50 of 0.6 nM. | ||||||||||||||||||||
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TizaterKib (Standard) | ≥98% | TizaterKib (Standard) is the analytical standard of TizaterKib (HY-111483). This product is intended for research and analytical applications. TizaterKib (AZD0364) is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1, compound example 18, has an IC50 of 0.6 nM. | ||||||||||||||||||||
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