2097509-40-3
2097509-40-3
Chemical Structure
Thalidomide-NH-PEG2-C2-NH-Boc
- CAS No.: 2097509-40-3
- Formula:C24H32N4O8
- Molecular Weight:504.53
IUPAC Name: tert-butyl (2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)carbamate
InChIKey: YMOKYFTVZVHRSA-UHFFFAOYSA-N
SMILES: O=C(OC(C)(C)C)NCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Biological Activity: Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the?Thalidomide?based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology[1].
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Thalidomide-NH-PEG2-C2-NH-Boc | 98.37% | Thalidomide-NH-PEG2-C2-NH-Boc is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the?Thalidomide?based cereblon ligand and a PEG linker used for dBRD9 (compound 6) synthesis. dBRD9 is a selective BRD9 probe PROTAC degrader for the study of BAF complex biology. | ||||||||||||||||||||
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