2097826-24-7
Chemical Structure
Yhhu-3792
- CAS No.: 2097826-24-7
- Formula:C24H24N4O2
- Molecular Weight:400.47
IUPAC Name: N2-(4-isopropylphenyl)-5-(3-methoxyphenoxy)quinazoline-2,4-diamine
InChIKey: PDGVGAAXMRKVPG-UHFFFAOYSA-N
SMILES: NC1=C2C(OC3=CC=CC(OC)=C3)=CC=CC2=NC(NC4=CC=C(C(C)C)C=C4)=N1
Biological Activity: Yhhu-3792 is a Notch activator. Yhhu-3792 enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 promotes the expression of Hes3 and Hes5. Yhhu-3792 increases the spatial and episodic memory abilities of mice. Yhhu-3792 can be used for the study of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Yhhu-3792 | 99.34% | Yhhu-3792 is a Notch activator. Yhhu-3792 enhances the self-renewal capability of neural stem cells (NSCs). Yhhu-3792 promotes the expression of Hes3 and Hes5. Yhhu-3792 increases the spatial and episodic memory abilities of mice. Yhhu-3792 can be used for the study of neurodegenerative diseases (such as Alzheimer's disease) or for neural regeneration after brain injury. | ||||||||||||||||||||
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References
- [1]. Lu H, et al. A Novel 2-Phenylamino-Quinazoline-Based Compound Expands the Neural Stem Cell Pool and Promotes the Hippocampal Neurogenesis and the Cognitive Ability of Adult Mice. Stem Cells. 2018 Aug;36(8):1273-1285. [Content Brief]
- [2]. Kunkanjanawan H, et al. Efficient large-scale expansion of cord blood-derived NK cells: leveraging lipopolysaccharide for enhanced NK cell production. Cytotherapy. 2025 Jun;27(6):782-789. [Content Brief]
