209984-57-6
209984-57-6
Chemical Structure
LY-411575
- CAS No.: 209984-57-6
- Formula:C26H23F2N3O4
- Molecular Weight:479.48
IUPAC Name: (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide
InChIKey: ULSSJYNJIZWPSB-CVRXJBIPSA-N
SMILES: O=C1[C@@H](NC([C@@H](NC([C@H](C2=CC(F)=CC(F)=C2)O)=O)C)=O)C3=CC=CC=C3C(C=CC=C4)=C4N1C
Biological Activity: LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with an IC50 of 0.39 nM.
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LY-411575 | 99.28% | LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with an IC50 of 0.39 nM. | ||||||||||||||||||||
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LY-411575 (Standard) | ≥98% | LY-411575 (Standard) is the analytical standard of LY-411575 (HY-50752). This product is intended for research and analytical applications. LY-411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), and also inhibits Notch S3 cleavage with an IC50 of 0.39 nM. | ||||||||||||||||||||
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