2101206-26-0
2101206-26-0
Chemical Structure
CLK1/4-IN-2
- CAS No.: 2101206-26-0
- Formula:C18H16FNO2S
- Molecular Weight:329.39
IUPAC Name: N-(3-fluorobenzyl)-5-methoxy-N-methylbenzo[b]thiophene-2-carboxamide
InChIKey: HHUOQHKKRABAQB-UHFFFAOYSA-N
SMILES: O=C(C=1SC=2C=CC(OC)=CC2C1)N(C)CC=3C=CC=C(F)C3
Biological Activity: CLK1/4-IN-2 is a selective CLK1/4 inhibitor, with an IC50 of 7 nM against CLK1 and an IC50 of 2.3 nM against CLK4. CLK1/4-IN-2 induces protein depletion in cancer cells and exhibits anticancer activity. CLK1/4-IN-2 can be used in research related to breast cancer, monocytic leukemia, bladder cancer, mammary adenocarcinoma and hepatocellular carcinoma[1].
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CLK1/4-IN-2 | CLK1/4-IN-2 is a selective CLK1/4 inhibitor, with an IC50 of 7 nM against CLK1 and an IC50 of 2.3 nM against CLK4. CLK1/4-IN-2 induces protein depletion in cancer cells and exhibits anticancer activity. CLK1/4-IN-2 can be used in research related to breast cancer, monocytic leukemia, bladder cancer, mammary adenocarcinoma and hepatocellular carcinoma. | |||||||||||||||||||||
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