210245-80-0
210245-80-0
Chemical Structure
Zonampanel
Synonym(s): YM 872
- CAS No.: 210245-80-0
- Formula:C13H9N5O6
- Molecular Weight:331.24
IUPAC Name: 2-(7-(1H-imidazol-1-yl)-6-nitro-2,3-dioxo-3,4-dihydroquinoxalin-1(2H)-yl)acetic acid
InChIKey: SPXYHZRWPRQLNS-UHFFFAOYSA-N
SMILES: O=C(N1CC(O)=O)C(NC(C1=C2)=CC([N+]([O-])=O)=C2N3C=CN=C3)=O
Biological Activity: Zonampanel (YM 872) is a selective antagonist of the glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Zonampanel | 99.02% | Zonampanel (YM 872) is a selective antagonist of the glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor. | ||||||||||||||||||||
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Nitraquazone | Nitraquazone (TVX 2706) is an anti-inflammatory and analgesic agent, belonging to the derivatives of Phenylbutazone (HY-B0230). Nitraquazone inhibits phosphodiesterase and enhances the elevation of intracellular cyclic adenosine monophosphate levels. Nitraquazone can be used in research related to anti-inflammation and analgesia. | |||||||||||||||||||||
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Ro 48-8587 | Ro 48-8587 is a selective AMPA receptor antagonist with an IC50 of 8 nM. Ro 48-8587 functionally inhibits AMPA receptor activity, blocks AMPA-induced depolarization of rat cortical wedges. Ro 48-8587 can be used for the research of ischaemia and seizures. | |||||||||||||||||||||
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Antibacterial agent 105 | Antibacterial agent 105 (Compound 17) is a phenanthrolinic analog of quinolones show antibacterial activity against M. tuberculosis with antibacterial activity (MIC90=2.64 μM). Antibacterial agent 105 exhibits antibacterial activities against different bacterial species with MIC90s of 11.18, 11.18, 0.70, 1.40, 44.70, and 22.35 μM for M. smegmatis, M. aurum, M. marinum, BCG, E. aerogenes and S. aureus, respectively. | |||||||||||||||||||||
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DNQX | 99.67% | DNQX (FG 9041), a quinoxaline derivative, is a selective, potent competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5, 2 and 40 μM for AMPA, kainate and NMDA receptors, respectively). | ||||||||||||||||||||
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NBQX | 99.82% | NBQX (FG9202) is a highly selective and competitive AMPA receptor antagonist. NBQX has neuroprotective and anticonvulsant activity. | ||||||||||||||||||||
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YM 900 | YM 900 is an AMPA receptor antagonist. | |||||||||||||||||||||
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YM90K | 98.32% | YM90K is a potent and selective AMPA receptor antagonist with a Ki of 84 nM. YM90K is less potent in inhibiting kainate (Ki of 2.2 μM) and NMDA (Ki of 37 μM) receptors. YM90K has neuroprotective actions. | ||||||||||||||||||||
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2,5-Di(1H-imidazol-1-yl)terephthalic acid | 2,5-Di(1H-imidazol-1-yl)terephthalic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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4'-(1H-Imidazol-1-yl)[1,1'-biphenyl]-3,5-dicarboxylic acid | 4'-(1H-Imidazol-1-yl)[1,1'-biphenyl]-3,5-dicarboxylic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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4,6-Di(1H-imidazol-1-yl)isophthalic acid | 4,6-Di(1H-imidazol-1-yl)isophthalic acid(4,6-Di-1H-imidazol-1-yl-1,3-benzenedicarboxylic acid) is a metal-organic framework (MOF). | |||||||||||||||||||||
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