2111-75-3
2111-75-3
Chemical Structure
(±)-Perillaldehyde
- CAS No.: 2111-75-3
- Formula:C10H14O
- Molecular Weight:150.22
IUPAC Name: 4-(prop-1-en-2-yl)cyclohex-1-ene-1-carbaldehyde
InChIKey: RUMOYJJNUMEFDD-UHFFFAOYSA-N
SMILES: CC(C1CCC(C=O)=CC1)=C
Biological Activity: (±)-Perillaldehyde has an antidepressant effect by modulating the olfactory nervous system in a mouse model of stress-induced depression. (±)-Perillaldehyde also has anti-inflammatory activity, inducing JNK activation in RAW264.7 cells and inhibiting the expression of TNF-α, with an IC50 of 171.7 μM[1][2].
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(±)-Perillaldehyde | 96.70% | (±)-Perillaldehyde has an antidepressant effect by modulating the olfactory nervous system in a mouse model of stress-induced depression. (±)-Perillaldehyde also has anti-inflammatory activity, inducing JNK activation in RAW264.7 cells and inhibiting the expression of TNF-α, with an IC50 of 171.7 μM. | ||||||||||||||||||||
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References
- [1]. N Ito, et al. Antidepressant-like Effect of l-perillaldehyde in Stress-induced Depression-like Model Mice through Regulation of the Olfactory Nervous System. Evid Based Complement Alternat Med. 2011:2011:512697. [Content Brief]
- [2]. Takuya Uemura, et al. Intestinal Anti-Inflammatory Activity of Perillaldehyde. J Agric Food Chem. 2018 Apr 4;66(13):3443-3448. [Content Brief]
