2119738-70-2
2119738-70-2
Chemical Structure
Tanfanercept
Synonym(s): HL036337; HBM9036
- CAS No.: 2119738-70-2
- Formula:N/A
- Molecular Weight:N/A
IUPAC Name: tert-butyl 2-bromo-4-methylthiazole-5-carboxylate
SMILES: [Tanfanercept]
Biological Activity: Tanfanercept (HL036337) is an TNF-α receptor fusion protein that targets TNF-α. Tanfanercept is effective in ameliorating corneal erosions in a dry eye (DE) mouse model[1][2].
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Tanfanercept | Tanfanercept (HL036337) is an TNF-α receptor fusion protein that targets TNF-α. Tanfanercept is effective in ameliorating corneal erosions in a dry eye (DE) mouse model. | |||||||||||||||||||||
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References
- [1]. Choi W, et al. The Effect of TNF-α Blocker HL036337 and Its Best Concentration to Inhibit Dry Eye Inflammation. Korean J Ophthalmol. 2016 Aug;30(4):302-8. [Content Brief]
- [2]. Dong Y, et al. TNF-α inhibitor tanfanercept (HBM9036) improves signs and symptoms of dry eye in a phase 2 trial in the controlled adverse environment in China. Int Ophthalmol. 2022 Aug;42(8):2459-2472. [Content Brief]
