212118-77-9
212118-77-9
Chemical Structure
FlAsH-EDT2
- CAS No.: 212118-77-9
- Formula:C24H18As2O5S4
- Molecular Weight:664.50
IUPAC Name: 4',5'-di(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one
InChIKey: AJNUQUGWNQHQDJ-UHFFFAOYSA-N
SMILES: O=C1OC2(C3=C(OC4=C2C=CC(O)=C4[As]5SCCS5)C([As]6SCCS6)=C(O)C=C3)C7=C1C=CC=C7
Biological Activity: FlAsH-EDT2 is a protein labeling reagent. FlAsH-EDT2 binds to Cys4 with high affinity and emits fluorescence. FlAsH-EDT2 can cross the cell membrane and enter the interior of the cell. FlAsH-EDT2 can only be used for labeling proteins with high concentration[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FlAsH-EDT2 | 98.98% | FlAsH-EDT2 is a protein labeling reagent. FlAsH-EDT2 binds to Cys4 with high affinity and emits fluorescence. FlAsH-EDT2 can cross the cell membrane and enter the interior of the cell. FlAsH-EDT2 can only be used for labeling proteins with high concentration. | ||||||||||||||||||||
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References
- [1]. Stroffekova K, et al. The protein-labeling reagent FLASH-EDT2 binds not only to CCXXCC motifs but also non-specifically to endogenous cysteine-rich proteins. Pflugers Arch. 2001 Sep;442(6):859-66. [Content Brief]
- [2]. Adams SR, et al. Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc. 2008;3(9):1527-34. [Content Brief]
