2124271-48-1
2124271-48-1
Chemical Structure
(-)-Nebivolol-d4 hydrochloride
- CAS No.: 2124271-48-1
- Formula:C22H22D4ClF2NO4
- Molecular Weight:445.92
IUPAC Name: (S)-1-((R)-6-fluorochroman-2-yl)-2-(((S)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl-1,1-d2)amino)ethan-2,2-d2-1-ol hydrochloride
InChIKey: JWEXHQAEWHKGCW-YNYGMEKVSA-N
SMILES: O[C@H]([C@]1([H])OC2=CC=C(F)C=C2CC1)C([2H])([2H])NC([2H])([2H])[C@H](O)[C@@]3([H])OC4=CC=C(F)C=C4CC3.Cl
Biological Activity: (-)-Nebivolol-d4 (hydrochloride) is the deuterium labeled (-)-Nebivolol hydrochloride[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(-)-Nebivolol-d4 hydrochloride | (-)-Nebivolol-d4 (hydrochloride) is the deuterium labeled (-)-Nebivolol hydrochloride. | |||||||||||||||||||||
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Nebivolol hydrochloride (Standard) | ≥98% | Nebivolol (hydrochloride) (Standard) is the analytical standard of Nebivolol (hydrochloride). This product is intended for research and analytical applications. Nebivolol (R 065824) hydrochloride is an orally active beta receptor blocker and has the high beta(1)-receptor affinity.Nebivolol hydrochloride has direct vasodilator properties and adrenergic blocking characteristics. Nebivolol hydrochloride can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease. | ||||||||||||||||||||
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Nebivolol hydrochloride | 99.94% | Nebivolol (R 065824) hydrochloride is an orally active beta receptor blocker and has the high beta(1)-receptor affinity.Nebivolol hydrochloride has direct vasodilator properties and adrenergic blocking characteristics. Nebivolol hydrochloride can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease. | ||||||||||||||||||||
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(Rac)-N-Benzyl Nebivolol-d4 | (Rac)-N-Benzyl Nebivolol-d4 is the deuterium labeled (Rac)-N-Benzyl Nebivolol. | |||||||||||||||||||||
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4-Hydroxy nebivolol hydrochloride | 4-Hydroxy nebivolol (4-OH nebivolol) hydrochloride is an active β-blocking hydroxylated metabolite of Nebivolol (HY-B0203). | |||||||||||||||||||||
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(+)-Nebivolol-d4 | (S,R,R,R)-Nebivolol-d4 is deuterium labeled (S,R,R,R)-Nebivolol. | |||||||||||||||||||||
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Desfluoro nebivolol | Desfluoro nebivolol is a desfluorinated Nebivolol (HY-B0203) isomer. Desfluoro nebivolol is a side product of the potent antihypertensive β-blocker Nebivolol. | |||||||||||||||||||||
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Nebivolol | 99.94% | Nebivolol (R 065824) is an orally active beta receptor blocker and has the high beta(1)-receptor affinity. Nebivolol has direct vasodilator properties and adrenergic blocking characteristics. Nebivolol can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease. | ||||||||||||||||||||
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(Rac)-Nebivolol | (Rac)-Nebivolol ((Rac)-R 065824) is a racemic isomer of Nebivolol. Nebivolol is a selective β1-adrenergic receptor antagonist with an IC50 value of 0.8 nM. Nebivolol can prevent up-regulation of Nox2/NADPH oxidase and lipoperoxidation in the early stages of ethanol-induced cardiac toxicity. Vasodilatory activity. | |||||||||||||||||||||
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(rac)-Nebivolol-d4 | (rac)-Nebivolol-d4 is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1- adrenergic receptor with IC50 of 0.8 nM. | |||||||||||||||||||||
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N-Nitroso nebivolol (mixture of diastereomers) | N-Nitroso nebivolol (mixture of diastereomers) is a nitrosamine and mutagenic. | |||||||||||||||||||||
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(Rac)-Nebivolol-d4 hydrochloride | (Rac)-Nebivolol-d4 hydrochloride is a labelled racemic Nebivolol. Nebivolol selectively inhibits β1-adrenergic receptor with an IC50 of 0.8 nM. | |||||||||||||||||||||
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