2126853-16-3
2126853-16-3
Chemical Structure
IDO1-IN-22
- CAS No.: 2126853-16-3
- Formula:C12H12BrFN6O3
- Molecular Weight:387.16
IUPAC Name: (Z)-N-(3-bromo-4-fluorophenyl)-4-(3-ethylureido)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
InChIKey: XSNUQYQJULXZFX-UHFFFAOYSA-N
SMILES: CCNC(NC1=NON=C1/C(NC2=CC=C(C(Br)=C2)F)=N/O)=O
Biological Activity: IDO1-IN-22 (Compound 3) is a IDO1 inhibitor (biochemical hIDO1 IC50: 67.4 nM, HeLa hIDO1 IC50: 17.6 nM). IDO1-IN-22 has excellent antitumor efficacy in LLC xenograft model, as well as desirable pharmacokinetic (PK) profile[1].
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IDO1-IN-22 | IDO1-IN-22 (Compound 3) is a IDO1 inhibitor (biochemical hIDO1 IC50: 67.4 nM, HeLa hIDO1 IC50: 17.6 nM). IDO1-IN-22 has excellent antitumor efficacy in LLC xenograft model, as well as desirable pharmacokinetic (PK) profile. | |||||||||||||||||||||
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