2133815-88-8
2133815-88-8
Chemical Structure
SG5-081
- CAS No.: 2133815-88-8
- Formula:C12H9N3O4
- Molecular Weight:259.22
InChIKey: MSHTVRYXGFREAN-UHFFFAOYSA-N
SMILES: O=C1N(C(C2)C(NC2=O)=O)C(C3=C1C=CC=C3N)=O
Biological Activity: SG5-081 is an IKZF3 Molecular glue degrader. SG5-081 mediates CRBN-dependent ubiquitination and proteasomal degradation of IKZF3. SG5-081 does not reduce CK1α levels. SG5-081 can be used for research on multiple myeloma[1].
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SG5-081 | SG5-081 is an IKZF3 Molecular glue degrader. SG5-081 mediates CRBN-dependent ubiquitination and proteasomal degradation of IKZF3. SG5-081 does not reduce CK1α levels. SG5-081 can be used for research on multiple myeloma. | |||||||||||||||||||||
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