2133852-18-1
2133852-18-1
Chemical Structure
Zastaprazan
Synonym(s): JP-1366
- CAS No.: 2133852-18-1
- Formula:C22H26N4O
- Molecular Weight:362.47
IUPAC Name: azetidin-1-yl(8-((2,6-dimethylbenzyl)amino)-2,3-dimethylimidazo[1,2-a]pyridin-6-yl)methanone
InChIKey: FEQFUBYYZYQTOJ-UHFFFAOYSA-N
SMILES: O=C(N1CCC1)C2=CN3C(C)=C(C)N=C3C(NCC4=C(C)C=CC=C4C)=C2
Biological Activity: Zastaprazan (JP-1366) is a proton pump inhibitor and a potent potassium-competitive acid blocker. Zastaprazan can be used in the research of gastrointestinal inflammatory diseases or gastric acid-related diseases such as gastroesophageal reflux disease[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Zastaprazan | 99.85% | Zastaprazan (JP-1366) is a proton pump inhibitor and a potent potassium-competitive acid blocker. Zastaprazan can be used in the research of gastrointestinal inflammatory diseases or gastric acid-related diseases such as gastroesophageal reflux disease. | ||||||||||||||||||||
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References
- [1]. Jeongmin Kim, et al. Imidazo[1,2-a]pyridine derivatives, methods for preparing the same and use thereof. WO2018008929A1. 2018-01-11.
- [2]. Oh JH, et al. Randomized, Double-Blind, Active-Controlled Phase 3 Study to Evaluate Efficacy and Safety of Zastaprazan Compared With Esomeprazole in Erosive Esophagitis. Am J Gastroenterol. 2025 Feb 1;120(2):353-361. [Content Brief]
