2135615-68-6
Chemical Structure
Contilisant
- CAS No.: 2135615-68-6
- Formula:C22H31N3O
- Molecular Weight:353.50
IUPAC Name: N-methyl-N-((1-methyl-5-(3-(piperidin-1-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine
InChIKey: NQDGCGNKNJWZHP-UHFFFAOYSA-N
SMILES: C#CCN(C)CC(N1C)=CC2=C1C=CC(OCCCN3CCCCC3)=C2
Biological Activity: Contilisant is a permeable antioxidant and neuroprotectant agent. Contilisant exhibits high nM affinity at H3R. Contilisant inhibits monoamine oxidases and cholinesterases. Contilisant has a binding affinity of 65.23 nM towards hS1R. Contilisant can significantly restore cognitive deficit induced by Aβ1-42 in the radial maze assay of Alzheimer’s animal model[1].
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Contilisant | Contilisant is a permeable antioxidant and neuroprotectant agent. Contilisant exhibits high nM affinity at H3R. Contilisant inhibits monoamine oxidases and cholinesterases. Contilisant has a binding affinity of 65.23 nM towards hS1R. Contilisant can significantly restore cognitive deficit induced by Aβ1-42 in the radial maze assay of Alzheimer’s animal model. | |||||||||||||||||||||
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