2139-03-9
2139-03-9
Chemical Structure
Δ1-Pyrroline-2-carboxylic acid
Synonym(s): Pyr2C
- CAS No.: 2139-03-9
- Formula:C5H7NO2
- Molecular Weight:113.11
IUPAC Name: 3,4-dihydro-2H-pyrrole-5-carboxylic acid
InChIKey: RHTAIKJZSXNELN-UHFFFAOYSA-N
SMILES: O=C(C1=NCCC1)O
Biological Activity: Δ1-Pyrroline-2-carboxylic acid (Pyr2C) is a cyclic imino acid involved in proline metabolism. Within cells, Δ1-Pyrroline-2-carboxylic acid can be directly reduced to proline, supporting the growth of proline-auxotrophic strains of Escherichia coli. Δ1-Pyrroline-2-carboxylic acid also serves as an intermediate in organic synthesis and can be used to synthesize L-pipecolic acid (HY-W012734)[1][2].
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Δ1-Pyrroline-2-carboxylic acid | Δ1-Pyrroline-2-carboxylic acid (Pyr2C) is a cyclic imino acid involved in proline metabolism. Within cells, Δ1-Pyrroline-2-carboxylic acid can be directly reduced to proline, supporting the growth of proline-auxotrophic strains of Escherichia coli. Δ1-Pyrroline-2-carboxylic acid also serves as an intermediate in organic synthesis and can be used to synthesize L-pipecolic acid (HY-W012734). | |||||||||||||||||||||
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References
- [1]. Mark L. Lewis, et al. The effect of pH on the solution structure of Δ1-pyrroline-2-carboxylic acid as revealed by NMR and electrospray mass spectroscopy. Bioorganic & Medicinal Chemistry Letters, June 1993.
- [2]. Kaja Stalder, et al. Biocatalytic Synthesis of l-Pipecolic Acid by a Lysine Cyclodeaminase: Batch and Flow Reactors. ChemCatChem 2024, e202301671.
