2140807-20-9
Chemical Structure
Thalidomide-4-NH-PEG1-COOH TFA
- CAS No.: 2140807-20-9
- Formula:C20H20F3N3O9
- Molecular Weight:503.38
IUPAC Name: 2,2,2-trifluoroacetic acid compound with 3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid (1:1)
InChIKey: IJDADJSYOBCJQK-UHFFFAOYSA-N
SMILES: O=C(O)CCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.O=C(O)C(F)(F)F
Biological Activity: Thalidomide-4-NH-PEG1-COOH TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-COOH TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-COOH TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
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Thalidomide-4-NH-PEG1-COOH TFA | Thalidomide-4-NH-PEG1-COOH TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-COOH TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-COOH TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules. | |||||||||||||||||||||
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