2143061-81-6
2143061-81-6
Chemical Structure
AZD-5991
- CAS No.: 2143061-81-6
- Formula:C35H34ClN5O3S2
- Molecular Weight:672.26
IUPAC Name: (Z)-16-chloro-11,21,25,61-tetramethyl-11H,21H,61H-10-oxa-4,8-dithia-1(7,3)-indola-2(4,3),6(3,5)-dipyrazola-9(3,1)-naphthalenacyclotridecaphane-12-carboxylic acid
InChIKey: KBQCEQAXHPIRTF-UHFFFAOYSA-N
SMILES: O=C(O)C1=C(CCCOC2=C(C=CC=C3)C3=CC4=C2)C5=C(N1C)C(C6=C(C)N(C)N=C6CSCC7=NN(C)C(CS4)=C7)=C(Cl)C=C5
Biological Activity: AZD-5991 is a potent and selective Mcl-1 inhibitor with an IC50 of 0.7 nM in FRET assay and a Kd of 0.17 nM in surface plasmon resonance (SPR) assay[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZD-5991 | 99.79% | AZD-5991 is a potent and selective Mcl-1 inhibitor with an IC50 of 0.7 nM in FRET assay and a Kd of 0.17 nM in surface plasmon resonance (SPR) assay. | ||||||||||||||||||||
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AZD-5991 (Standard) | ≥98% | AZD-5991 (Standard) is the analytical standard of AZD-5991 (HY-101533). This product is intended for research and analytical applications. AZD-5991 is a potent and selective Mcl-1 inhibitor with an IC50 of 0.7 nM in FRET assay and a Kd of 0.17 nM in surface plasmon resonance (SPR) assay. | ||||||||||||||||||||
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