214491-43-7
214491-43-7
Chemical Structure
DiFMUP
Synonym(s): 6,8-Difluoro-4-methylumbelliferyl phosphate
- CAS No.: 214491-43-7
- Formula:C10H7F2O6P
- Molecular Weight:292.13
IUPAC Name: 6,8-difluoro-4-methyl-2-oxo-2H-chromen-7-yl dihydrogen phosphate
InChIKey: DZANYXOTJVLAEE-UHFFFAOYSA-N
SMILES: O=P(OC1=C(C(OC2=O)=C(C(C)=C2)C=C1F)F)(O)O
Biological Activity: DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DiFMUP | 98.86% | DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader. | ||||||||||||||||||||
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References
- [1]. Gee KR, et, al. Fluorogenic substrates based on fluorinated umbelliferones for continuous assays of phosphatases and beta-galactosidases. Anal Biochem. 1999 Aug 15;273(1):41-8. [Content Brief]
- [2]. Welte S, et, al. 6,8-Difluoro-4-methylumbiliferyl phosphate: a fluorogenic substrate for protein tyrosine phosphatases. Anal Biochem. 2005 Mar 1;338(1):32-8. [Content Brief]
