2145123-44-8
Chemical Structure
Clervonafusp alfa
Synonym(s): VAL-1221
- CAS No.: 2145123-44-8
- Formula:N/A
- Molecular Weight:N/A
IUPAC Name: (R)-4-(1-aminoethyl)-3-(trifluoromethyl)benzonitrile
SMILES: [Clervonafusp alfa]
Biological Activity: Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha glucosidase (rhGAA), the former utilizing the nucleoside transporter ENT-2 to gain access to the cytosol, and the latter enters lysosomes via mannose-6-phosphate receptors (M6PRs). Clervonafusp alfa can be used for late-onset Pompe disease research[1].
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Clervonafusp alfa | Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha glucosidase (rhGAA), the former utilizing the nucleoside transporter ENT-2 to gain access to the cytosol, and the latter enters lysosomes via mannose-6-phosphate receptors (M6PRs). Clervonafusp alfa can be used for late-onset Pompe disease research. | |||||||||||||||||||||
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