2161364-69-6
2161364-69-6
Chemical Structure
HBV-IN-25
- CAS No.: 2161364-69-6
- Formula:C18H14ClNO4
- Molecular Weight:343.76
IUPAC Name: (R)-1-(5-chloro-9-oxo-9H-xanthen-3-yl)pyrrolidine-3-carboxylic acid
InChIKey: DHVRTFMBTRRBRG-SNVBAGLBSA-N
SMILES: O=C([C@H]1CN(C2=CC(OC3=C4C=CC=C3Cl)=C(C=C2)C4=O)CC1)O
Biological Activity: HBV-IN-25 is a good potency, orally active novel HBV cccDNA reducer. HBV-IN-25 has anti-HBeAg potency and anti-HBV activity with IC50 values of 0.58 μM and 1.15 μM, respectively. HBV-IN-25 has good aqueous solubility (LYSA＞452 μg/mL) and good PK property with no cellular toxicity[1].
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HBV-IN-25 | HBV-IN-25 is a good potency, orally active novel HBV cccDNA reducer. HBV-IN-25 has anti-HBeAg potency and anti-HBV activity with IC50 values of 0.58 μM and 1.15 μM, respectively. HBV-IN-25 has good aqueous solubility (LYSA＞452 μg/mL) and good PK property with no cellular toxicity. | |||||||||||||||||||||
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