2162982-11-6
2162982-11-6
Chemical Structure
BAY-218
Synonym(s): AHR antagonist 1
- CAS No.: 2162982-11-6
- Formula:C20H17ClFN3O3
- Molecular Weight:401.82
IUPAC Name: (S)-6-(4-chlorophenyl)-2-(3-fluorophenyl)-N-(1-hydroxypropan-2-yl)-3-oxo-2,3-dihydropyridazine-4-carboxamide
InChIKey: RFGRNBWAUZSMBN-LBPRGKRZSA-N
SMILES: O=C(C1=CC(C2=CC=C(Cl)C=C2)=NN(C3=CC=CC(F)=C3)C1=O)N[C@@H](C)CO
Biological Activity: BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses[1].
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BAY-218 | 99.78% | BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses. | ||||||||||||||||||||
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BAY-218 (Standard) | ≥98% | BAY-218 (Standard) is the analytical standard of BAY-218 (HY-111449). This product is intended for research and analytical applications. BAY-218 (AHR antagonist 1) is an aryl hydrocarbon receptor (AHR) antagonist. BAY-218 has AHR inhibitory activity with an IC50 of 39.9 nM in in U87 glioblastoma cells. BAY-218 can be used for the research of cancer or conditions with dysregulated immune responses. | ||||||||||||||||||||
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