2165325-42-6
2165325-42-6
Chemical Structure
VU6010608
- CAS No.: 2165325-42-6
- Formula:C18H15F3N4O4
- Molecular Weight:408.33
IUPAC Name: N-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-3,4-dimethoxybenzamide
InChIKey: YCDOKDADFOBKIL-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(OC(F)(F)F)=CC=C1N2N=CN=C2)C3=CC=C(OC)C(OC)=C3
Biological Activity: VU6010608 is a blood-brain barrier-crossing mGlu7 negative allosteric modulator (IC50 = 0.76 μM). VU6010608 can block long-term enhancement (LTP) of SC-CA1 synapses in mouse brain slices induced by high-frequency stimulation. VU6010608 can be used for research on neurological diseases[1].
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VU6010608 | VU6010608 is a blood-brain barrier-crossing mGlu7 negative allosteric modulator (IC50 = 0.76 μM). VU6010608 can block long-term enhancement (LTP) of SC-CA1 synapses in mouse brain slices induced by high-frequency stimulation. VU6010608 can be used for research on neurological diseases. | |||||||||||||||||||||
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