2166378-92-1
Chemical Structure
Glucocorticoid receptor agonist-2
- CAS No.: 2166378-92-1
- Formula:C34H35F2NO7
- Molecular Weight:607.64
IUPAC Name: (2S,6aS,6bR,7S,8aS,8bS,10R,11aR,12aS,12bS)-10-(4-(3-aminophenoxy)phenyl)-2,6b-difluoro-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
InChIKey: LCDCPIOGHJGDBP-APTODLHGSA-N
SMILES: [H][C@]1(C[C@]2(O[C@H](O[C@]23C(CO)=O)C4=CC=C(OC5=CC(N)=CC=C5)C=C4)[H])[C@@]6(C[C@@H](C7=CC(C=C[C@@]7([C@](F)6[C@@H](O)C[C@@]13C)C)=O)F)[H]
Biological Activity: Glucocorticoid receptor agonist-2 (compound 21) is an glucocorticoid receptor agonist with an IC50 value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Glucocorticoid receptor agonist-2 | 95.46% | Glucocorticoid receptor agonist-2 (compound 21) is an glucocorticoid receptor agonist with an IC50 value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373. | ||||||||||||||||||||
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