2166616-74-4
2166616-74-4
Chemical Structure
(Rac)-LY-3381916
Synonym(s): (Rac)-IDO1-IN-5
- CAS No.: 2166616-74-4
- Formula:C23H25FN2O3
- Molecular Weight:396.45
IUPAC Name: 4-fluoro-N-(1-(1-(tetrahydro-2H-pyran-4-carbonyl)indolin-5-yl)ethyl)benzamide
InChIKey: NUBWFWVVKLRSHS-UHFFFAOYSA-N
SMILES: O=C(NC(C1=CC2=C(N(C(C3CCOCC3)=O)CC2)C=C1)C)C4=CC=C(F)C=C4
Biological Activity: (Rac)-LY-3381916 ((Rac)-IDO1-IN-5; Example 1) is a racemate of LY-3381916[1]. LY-3381916 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[2].
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(Rac)-LY-3381916 | 99.12% | (Rac)-LY-3381916 ((Rac)-IDO1-IN-5; Example 1) is a racemate of LY-3381916. LY-3381916 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1. | ||||||||||||||||||||
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(Rac)-LY-3381916 (Standard) | ≥98% | (Rac)-LY-3381916 (Standard) is the analytical standard of (Rac)-LY-3381916 (HY-111540A). This product is intended for research and analytical applications. (Rac)-LY-3381916 ((Rac)-IDO1-IN-5; Example 1) is a racemate of LY-3381916. LY-3381916 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacKing heme rather than mature heme-bound IDO1. | ||||||||||||||||||||
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