2170-03-8
Chemical Structure
Itaconic anhydride
- CAS No.: 2170-03-8
- Formula:C5H4O3
- Molecular Weight:112.08
IUPAC Name: 3-methylenedihydrofuran-2,5-dione
InChIKey: OFNISBHGPNMTMS-UHFFFAOYSA-N
SMILES: O=C(O1)C(CC1=O)=C
Biological Activity: Itaconic anhydride is a bio-based organic acid anhydride compound that can be produced by dehydration of itaconic acid or pyrolysis of citric acid. Itaconic anhydride can be widely used in the development of biodegradable materials, synthesis of hydrogels, crosslinking modification of polymer resins, and construction of pharmaceutical intermediates[1][2][3][4][5].
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Itaconic anhydride | Itaconic anhydride is a bio-based organic acid anhydride compound that can be produced by dehydration of itaconic acid or pyrolysis of citric acid. Itaconic anhydride can be widely used in the development of biodegradable materials, synthesis of hydrogels, crosslinking modification of polymer resins, and construction of pharmaceutical intermediates. | |||||||||||||||||||||
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References
- [1]. Li XN, et al. Analysis of volatile fractions of Schisandra chinensis (Turcz.) Baill. using GC-MS and chemometric resolution. Phytochemical analysis : PCA. 2003;14(1):23-33.
- [2]. Wang Q, et al. Targeting hepatic macrophage metabolic reprogramming via itaconate-functionalized nanomedicine for acute liver injury. Chem Eng J. 2026 Aug 1;542:178234.
- [3]. Gao R, et al. Immunomodulatory Programming of Circulating Myeloid Cells via Itaconic Acid Liposomes to Mitigate Myocarditis. ACS nano. 2026 Jan 13;20(1):1205-1224.
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[4]. Shang S, et al. Synthesis and characterization of itaconic anhydride and stearyl methacrylate copolymers. Polymer. 2009 Jul 3;50(14):3119-27.
- [5]. Feldhusen J, et al. Domain-specific functionalization of cellulose fibers via itaconic anhydride-mediated esterification. Cellulose. 2026 Mar 24;33:3143-59. doi: [10.1007/s10570-026-07011-5](https://doi.org/10.1007/s10570-026-07011-5)