2172819-74-6
2172819-74-6
Chemical Structure
(S,R,S)-AHPC-C4-COOH
Synonym(s): VH032-C4-COOH
- CAS No.: 2172819-74-6
- Formula:C28H38N4O6S
- Molecular Weight:558.69
IUPAC Name: 6-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-6-oxohexanoic acid
InChIKey: DKSZOQIYZOVHOL-TYBLODHISA-N
SMILES: OC(CCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)=O)=O)=O
Biological Activity: (S,R,S)-AHPC-C4-COOH (VH032-C4-COOH) (linker 45) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-targeted PROTAC[1].
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(S,R,S)-AHPC-C4-COOH | 95.92% | (S,R,S)-AHPC-C4-COOH (VH032-C4-COOH) (linker 45) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-targeted PROTAC. | ||||||||||||||||||||
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