2172819-75-7
2172819-75-7
Chemical Structure
VH 032 amide-alkylC6-acid
Synonym(s): (S,R,S)-AHPC-CO-C6-COOH
- CAS No.: 2172819-75-7
- Formula:C30H42N4O6S
- Molecular Weight:586.74
IUPAC Name: 8-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-8-oxooctanoic acid
InChIKey: DCNOFAZZHMWMEI-QSEAXJEQSA-N
SMILES: O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCCCC(O)=O)=O)=O)C[C@H](O)C3
Biological Activity: VH 032 amide-alkylC6-acid ((S,R,S)-AHPC-CO-C6-COOH) is a VH032 analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH 032 amide-alkylC6-acid can be used in the synthesis of PROTACs[1].
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VH 032 amide-alkylC6-acid | VH 032 amide-alkylC6-acid ((S,R,S)-AHPC-CO-C6-COOH) is a VH032 analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH 032 amide-alkylC6-acid can be used in the synthesis of PROTACs. | |||||||||||||||||||||
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