2173508-07-9
Chemical Structure
CGRP antagonist 7
- CAS No.: 2173508-07-9
- Formula:C30H32FN5O3
- Molecular Weight:529.61
IUPAC Name: N-(2-((2R,5S)-2-(2-cyanopropan-2-yl)-5-(3-fluorophenyl)pyrrolidin-1-yl)-2-oxoethyl)-3-methyl-4-((6-methyl-3-oxo-2,3-dihydropyridazin-4-yl)methyl)benzamide
InChIKey: BRTUOYAEDFAFHK-IZZNHLLZSA-N
SMILES: CC1=NNC(C(CC2=CC=C(C=C2C)C(NCC(N3[C@@H](CC[C@@H]3C(C)(C#N)C)C4=CC(F)=CC=C4)=O)=O)=C1)=O
Biological Activity: CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki of 0.029 nM. CGRP antagonist 7 Inhibit the production of cyclic adenosine monophosphate (cAMP) with an IC50 of 1.5 nM. CGRP antagonist 7 can be used for the study of migraine[1].
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CGRP antagonist 7 | CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki of 0.029 nM. CGRP antagonist 7 Inhibit the production of cyclic adenosine monophosphate (cAMP) with an IC50 of 1.5 nM. CGRP antagonist 7 can be used for the study of migraine. | |||||||||||||||||||||
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